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Dirk Schadendorf Selected Research

Vaccines

5/2023Multispectral optoacoustic tomography to differentiate between lymph node metastases and coronavirus-19 vaccine-associated lymphadenopathy.
1/2017Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.
6/2010Clinical and immunological responses in metastatic melanoma patients vaccinated with a high-dose poly-epitope vaccine.
7/2008Human CD4+ T lymphocytes recognize a vascular endothelial growth factor receptor-2-derived epitope in association with HLA-DR.
1/2007Identification of different tumor escape mechanisms in several metastases from a melanoma patient undergoing immunotherapy.
11/2005A novel strategy for the discovery of MHC class II-restricted tumor antigens: identification of a melanotransferrin helper T-cell epitope.
10/2005Melanoma cell necrosis facilitates transfer of specific sets of antigens onto MHC class II molecules of dendritic cells.
3/2002Comparative assessment of TCRBV diversity in T lymphocytes present in blood, metastatic lesions, and DTH sites of two melanoma patients vaccinated with an IL-7 gene-modified autologous tumor cell vaccine.

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Dirk Schadendorf Research Topics

Disease

440Melanoma (Melanoma, Malignant)
04/2024 - 01/2002
269Neoplasms (Cancer)
05/2024 - 01/2002
88Neoplasm Metastasis (Metastasis)
05/2024 - 03/2002
37Disease Progression
05/2024 - 06/2004
28Skin Neoplasms (Skin Cancer)
05/2023 - 01/2002
20Brain Neoplasms (Brain Tumor)
09/2023 - 02/2008
19Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2024 - 03/2007
16Merkel Cell Carcinoma
12/2023 - 01/2017
8Uveal melanoma
10/2023 - 05/2013
8Exanthema (Rash)
10/2023 - 06/2011
8Lymphatic Metastasis
05/2023 - 08/2003
8Inflammation (Inflammations)
01/2022 - 10/2011
7Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2024 - 12/2012
7Basal Cell Carcinoma (Rodent Ulcer)
12/2022 - 08/2014
7Neutropenia
01/2021 - 11/2012
6Fatigue
03/2024 - 06/2009
6Nausea
10/2023 - 06/2011
6Fever (Fevers)
01/2023 - 11/2014
6Hypertension (High Blood Pressure)
11/2022 - 01/2017
6Body Weight (Weight, Body)
10/2019 - 01/2010
6Breast Neoplasms (Breast Cancer)
01/2018 - 11/2008
6Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
04/2008 - 04/2003
5Dermatitis
03/2024 - 03/2010
5Diarrhea
10/2023 - 06/2009
5COVID-19
01/2023 - 01/2021
5Infections
01/2021 - 07/2006
5Colitis
11/2019 - 08/2015
5Arthralgia (Joint Pain)
10/2018 - 06/2011
5Keratoacanthoma
01/2018 - 11/2010
4Pain (Aches)
02/2024 - 05/2015

Drug/Important Bio-Agent (IBA)

85Immune Checkpoint InhibitorsIBA
03/2024 - 01/2016
57IpilimumabIBA
12/2023 - 02/2010
55Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
04/2024 - 02/2007
50AntigensIBA
01/2023 - 01/2002
49NivolumabIBA
03/2024 - 01/2015
45Biomarkers (Surrogate Marker)IBA
01/2024 - 08/2005
44Proteins (Proteins, Gene)FDA Link
03/2024 - 05/2002
39pembrolizumabIBA
03/2024 - 01/2015
33dabrafenibIBA
09/2023 - 11/2012
32trametinibIBA
10/2023 - 07/2012
30VemurafenibIBA
04/2024 - 11/2010
25DNA (Deoxyribonucleic Acid)IBA
01/2023 - 11/2002
22Peptides (Polypeptides)IBA
01/2020 - 03/2002
21AntibodiesIBA
01/2022 - 03/2004
18LigandsIBA
01/2023 - 03/2004
17Neoplasm Antigens (Tumor Antigens)IBA
11/2021 - 03/2002
17Dacarbazine (DIC)FDA LinkGeneric
11/2020 - 09/2005
16InterferonsIBA
01/2023 - 09/2008
16EpitopesIBA
10/2021 - 03/2002
15binimetinibIBA
04/2024 - 03/2013
15Monophenol Monooxygenase (Tyrosinase)IBA
01/2022 - 03/2002
14L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
05/2023 - 12/2007
14Phosphotransferases (Kinase)IBA
01/2023 - 08/2004
13CytokinesIBA
01/2023 - 01/2002
13Messenger RNA (mRNA)IBA
01/2023 - 07/2002
12encorafenibIBA
04/2024 - 01/2018
12Cisplatin (Platino)FDA LinkGeneric
03/2016 - 03/2002
10Monoclonal AntibodiesIBA
03/2024 - 04/2003
9Programmed Cell Death 1 ReceptorIBA
01/2023 - 01/2015
9Mitogen-Activated Protein KinasesIBA
05/2019 - 02/2011
8cemiplimabIBA
03/2024 - 01/2018
8RNA (Ribonucleic Acid)IBA
10/2023 - 01/2017
8VaccinesIBA
05/2023 - 03/2002
8B7-H1 AntigenIBA
01/2023 - 01/2017
8Differentiation AntigensIBA
01/2022 - 08/2004
7Creatine Kinase (Creatine Phosphokinase)IBA
10/2023 - 03/2013
7Telomerase (Telomerase Reverse Transcriptase)IBA
01/2023 - 01/2013
7Transcription Factors (Transcription Factor)IBA
01/2022 - 02/2011
7MicroRNAs (MicroRNA)IBA
01/2021 - 01/2012
7Interferon-alpha (Interferon Alfa)IBA
01/2014 - 08/2003
6relatlimabIBA
10/2023 - 01/2022
6HhAntag691IBA
04/2022 - 08/2014
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 02/2009
6Adenosine Triphosphate (ATP)IBA
02/2021 - 07/2003
6Complementary DNA (cDNA)IBA
12/2019 - 03/2003
6MART-1 AntigenIBA
01/2018 - 08/2004
6EnzymesIBA
01/2017 - 01/2003
6AutoantibodiesIBA
09/2013 - 01/2007
6Etoposide (VP 16)FDA LinkGeneric
12/2006 - 03/2002
5Proteasome Endopeptidase Complex (Proteasome)IBA
12/2023 - 05/2002
5Lipase (Acid Lipase)FDA Link
10/2023 - 11/2012
5TransducinIBA
01/2020 - 03/2007
5Microphthalmia-Associated Transcription FactorIBA
01/2019 - 11/2007
5Interferon alpha-2 (Roferon-A)FDA Link
05/2018 - 08/2003
5ParaffinIBA
01/2018 - 04/2007
5Interleukin-2 (IL2)IBA
12/2015 - 03/2002
5HLA-DR Antigens (HLA-DR)IBA
03/2014 - 06/2004
5Vindesine (Vindesin)IBA
12/2011 - 03/2002
5HLA-A*02:01 antigenIBA
10/2010 - 05/2002
4T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2023 - 11/2006
4CTLA-4 AntigenIBA
12/2020 - 02/2010
4Type 6 Cyclic Nucleotide PhosphodiesterasesIBA
01/2020 - 03/2007

Therapy/Procedure

226Therapeutics
05/2024 - 03/2002
87Immunotherapy
04/2024 - 01/2002
30Drug Therapy (Chemotherapy)
01/2022 - 01/2003
16Radiotherapy
10/2022 - 05/2004
9Aftercare (After-Treatment)
05/2023 - 04/2007
8Lymph Node Excision (Lymph Node Dissection)
01/2022 - 02/2008
4Metastasectomy
03/2022 - 10/2008
4Retreatment
01/2021 - 04/2013